Research Archives - Lewy Body Dementia Association

Why Men and Women with REM Sleep Behavior Disorder (RBD) May Face Different Dementia Risks

December 2, 2025 Men and women who act out their dreams at night may not face the same risks for dementia later in life. A new international study finds that […]

Research: Spotlight on Caregiving

November 3, 2025 In recognition of National Family Caregivers Month we are spotlighting research studies for care partners. If you or someone you provide care for is participating in a […]

I-Care-Rural Pilot

The I-CARE-Rural pilot study is evaluating whether the Brain CareNotes app is usable, acceptable, and effective for rural caregivers of individuals living with Alzheimer’s disease and Related Dementias (ADRD). The […]

Caregiver Bootcamp

This study aims to create and test a prototype educational program for family and friends of people who have been recently diagnosed with Alzheimer’s disease or related dementias. The program […]

Online Study Examines Daily Well-being of Caregivers for Lewy Body Dementia

September 30, 2025 Lewy body dementia (LBD) includes Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB). Lewy Body dementia it is the second most common form of progressive […]

Data from Full Extension Phase of RewinD-LB Trial Continue to Appear Promising

September 03, 2025 New data from the full 32-week open-label extension phase of the RewinD-LB trial continue to suggest that the study drug, neflamapimod, may slow cognitive decline in dementia […]

Trial Results: Ambroxol Safe in PDD, But No Clear Evidence of Benefit

August 1, 2025 Scientists have been studying a kind of cough medicine called ambroxol to determine if it might be a promising treatment for Parkinson’s disease dementia (PDD), one of […]

Gut Health and Parkinson’s Disease Dementia: A Hidden Connection?

July 1, 2025 Is there a connection between bacteria in the mouth and gut and the development of dementia in Parkinson’s disease? New research may shed light. Cognitive decline and […]

Testing a Caregiver Intervention: Initial Findings from the PERSEVERE Study

June 3, 2025 Lewy Body dementia (LBD) includes Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB). As the disease progresses, people with LBD need assistance that is not […]

New RewinD-LB Trial Results Show Promise

March 19, 2025 Earlier this month, CervoMed Pharmaceuticals reported data from an open-label extension phase of the RewinD-LB trial suggesting that the study drug, neflamapimod, may slow cognitive decline in […]

New imaging study reveals that energy use in the brain begins to decline early in DLB

January 5, 2025 A new research paper from Mayo Clinic and the Karolinska Institutet suggests that the brain’s energy use levels decline measurably early in the course of the disease. […]

SHIMMER Trial Reports Positive Results

December 18, 2024 This week Cognition Therapeutics reported encouraging topline results from their Phase 2 clinical trial of CT1812, an investigational drug being studied in people with dementia with Lewy […]

Trial Results – Experimental Drug Shows Promising Results in Phase 2 Trial

November 14, 2024 Clinical trial results reported at a recent scientific conference suggest that the drug nilotinib may improve outcomes in people with dementia with Lewy bodies (DLB). Nilotinib is […]

LBD Clinical Trials around the World

November 5, 2024 2024 has been an exciting year for clinical trials for people with Lewy body dementia (LBD). Over the past year, you have heard a lot from the […]

Does kidney injury increase risk for LBD?

September 26, 2024 A new study published in the medical research journal Neurology suggests that sudden worsening of kidney function (referred to as “acute kidney injury”) may nearly double the […]

Special Research Topic: Right of Withdrawal – What Research Participants Need to Know

September 04, 2024 Clinical trials are the key to unlocking future treatments and preventive strategies for Lewy body dementia (LBD). Only by testing new medications in controlled experiments, called trials, […]

Eye on Prevention: Clues from Prostate Therapy

August 05, 2024 According to new research from the University of Iowa, medications used for prostate enlargement may provide clues to future strategies to prevent dementia with Lewy bodies (DLB). […]

New Research Suggests Skin Test Can Detect Dementia with Lewy Bodies

May 29, 2024 Many people who have dementia with Lewy bodies (DLB) experience delay and difficulty with receiving an accurate diagnosis, often seeing multiple specialists before being correctly diagnosed. In […]

New Research Supports Nuplazid (Pimavanserin) Use in Parkinson’s Disease Dementia

March 18, 2024 Hallucinations and delusions (also called psychosis) are prominent features of Lewy body dementia (LBD), occurring in both dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD). […]

The U.S. Based DIAMOND Lewy™ Management Toolkit

Originally developed in the UK for dissemination via the National Health Service, the Diamond Lewy™ Management Toolkit provides a comprehensive overview of the management of the complex symptoms of Lewy body […]